1414851-55-0Relevant articles and documents
Synthesis of an advanced precursor of Rivastigmine: Cinchona-derived quaternary ammonium salts as organocatalysts for stereoselective imine reductions
Genoni, Andrea,Benaglia, Maurizio,Mattiolo, Emanuele,Rossi, Sergio,Raimondi, Laura,Barrulas, Pedro C.,Burke, Anthony J.
, p. 5752 - 5756 (2015)
The enantioselective reduction of ketoimines has been successfully realized, using trichlorosilane as the stoichiometric reducing agent in the presence of catalytic amounts of a Lewis base, specifically a Cinchona derivative. For the first time, a novel c