1415426-34-4

Basic information

• Product Name: 2-(4-bromophenyl)-5-n-butylfuran
• Synonyms: 2-(4-bromophenyl)-5-n-butylfuran
• CAS NO: 1415426-34-4
• Molecular Weight: 279.176
• Mol File: 1415426-34-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(4-bromophenyl)-5-n-butylfuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-bromophenyl)-5-n-butylfuran(1415426-34-4)
• EPA Substance Registry System: 2-(4-bromophenyl)-5-n-butylfuran(1415426-34-4)

Safety Data

• Hazardous Substances Data: 1415426-34-4(Hazardous Substances Data)

Upstream product

• 628-71-7 1-Heptyne 
• 586-75-4 4-chlorobenzoyl chloride 
• 4466-24-4 2-Butylfuran 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 1415426-05-9 (E)-1-(4-bromophenyl)-3-chlorooct-2-en-1-one 

Relevant articles and documents

Tandem Transformations via Friedel-Crafts Acylation Followed by a Ring-Expansion, Ring-Opening, and Cycloisomerization Sequence

A tandem synthetic route to a diverse array of cyclic compounds has been developed from Friedel-Crafts acylation of alkynes followed by the microwave irradiation of β-chlorovinyl ketone intermediates. The stereoisomeric β-chlorovinyl ketone intermediates smoothly underwent a thermal α-vinyl enolization and ring expansion to vinyl and carbocyclic furans as well as cyclopetene derivatives in good to excellent yields without the need for any catalysts.

Benzenesulfonyl chlorides: Alternative coupling partners for regiocontrolled palladium-catalyzed direct desulfitative 5-arylation of furans

The reactivity of furan derivatives in palladium-catalyzed desulfitative arylation was studied. Alkyl-substituted furan derivatives were successfully coupled with a variety of benzenesulfonyl chlorides using a phosphine-free catalyst; regioselective arylation at C5 of the furan was observed in all cases. This reaction tolerates a wide variety of substituents on the benzenesulfonyl derivative. It should be noted that even bromo- and iodobenzenesulfonyl chlorides were successfully coupled with furan derivatives without cleavage of the C-Br or C-I bonds, thus allowing further transformations. The use of these reactants demonstrates the potential of benzenesulfonyl chlorides as coupling partners to access to functionalized 5-arylfurans.

Studies on elimination pathways of β-halovinyl ketones leading to allenyl and propargyl ketones and furans under the action of mild bases

The elimination pathway of stereochemically defined β-halovinyl ketones has been investigated using a mild base, NEt3, leading to the formation of allenyl ketones and propargyl ketones. A preferential α-vinyl enolization of (E)-β-chlorovinyl ke