141557-08-6Relevant articles and documents
Preliminary study of the total synthesis of Bao Gong Teng A analogs using 8-benzyl-2-oxo-8-azabicyclo[3.2.1]-Oct-3-ene-6-endo/exo- and 7- endo/exo-carbonitrile
Rézel, Stéphane,Estour, Fran?ois,Canitrot, Damien,Bejan Voinea, Elena V.,Chezal, Jean-M.,Lartigue, Claire,Blache, Yves,Gueiffier, Alain,Dauphin, Gérard,Teulade, Jean C.,Chavignon, Olivier
, p. 989 - 1002 (2007/10/03)
The use of four cycloadducts from the Katritzky reaction for subsequent preparation of Bao Gong Teng A analogs was studied. We show that the reduction of 2-oxo-8-azabicyclo[3.2.1]octanes (1-4) to alcohols allows the 2- exo/endo isomerism to be exploited.