1415582-79-4Relevant articles and documents
Total syntheses of kealiinines A-C
Das, Jayanta,Koswatta, Panduka B.,Jones, J. Daniel,Yousufuddin, Muhammed,Lovely, Carl J.
supporting information, p. 6210 - 6213 (2013/02/23)
Short total syntheses of the Leucetta-derived alkaloids, kealiinines A-C, have been accomplished using an intramolecular Friedel-Crafts-dehydration sequence of a bis benzylic diol. The precursor diol was obtained through a series of position-specific Grignard reactions from 1-methyl-4,5- diiodoimidazole. C2-Azidation and hydrogenation of the azide then provided the reported structures of kealiinines A-C. While the 1H NMR data did not completely match for these materials, the HPLC data were consistent with the assigned structure of these alkaloids.