1415634-37-5

Basic information

• Product Name: trideuteromethyl ((S)-1-(2-((2S,3S)-3-((S)-2-amino-4-tertbutyldimethylsilyloxy-3,3-dimethylbutanamido)-2-hydroxy-4-phenylbutyl)-2-(4-(pyridin-2-yl)benzyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate
• Synonyms: trideuteromethyl ((S)-1-(2-((2S,3S)-3-((S)-2-amino-4-tertbutyldimethylsilyloxy-3,3-dimethylbutanamido)-2-hydroxy-4-phenylbutyl)-2-(4-(pyridin-2-yl)benzyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate
• CAS NO: 1415634-37-5
• Molecular Weight: 780.068
• Mol File: 1415634-37-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: trideuteromethyl ((S)-1-(2-((2S,3S)-3-((S)-2-amino-4-tertbutyldimethylsilyloxy-3,3-dimethylbutanamido)-2-hydroxy-4-phenylbutyl)-2-(4-(pyridin-2-yl)benzyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: trideuteromethyl ((S)-1-(2-((2S,3S)-3-((S)-2-amino-4-tertbutyldimethylsilyloxy-3,3-dimethylbutanamido)-2-hydroxy-4-phenylbutyl)-2-(4-(pyridin-2-yl)benzyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate(1415634-37-5)
• EPA Substance Registry System: trideuteromethyl ((S)-1-(2-((2S,3S)-3-((S)-2-amino-4-tertbutyldimethylsilyloxy-3,3-dimethylbutanamido)-2-hydroxy-4-phenylbutyl)-2-(4-(pyridin-2-yl)benzyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate(1415634-37-5)

Safety Data

• Hazardous Substances Data: 1415634-37-5(Hazardous Substances Data)

Upstream product

• 1415634-31-9 C₂₀H₃₃NO₅Si 
• 1415634-36-4 ((5S,8S,9S,14S)-8-benzyl-9-hydroxy-1-phenyl-5-(1-tertbutyldimethylsilyloxy-2-methylpropan-2-yl)-15,15-dimethyl-3,6,13-trioxo-11-(4-(pyridin-2-yl)benzyl)-2-oxa-4,7,11,12-tetraazahexadecan-14-yl)carbamic acid trideuteromethyl ester 
• 157717-57-2 (3R)-4,4-dimethyl-2-oxotetrahydrofuran-3-yl trifluoromethanesulfonate 

Downstream Products

• 1415634-38-6 ((5S,8S,9S,14S)-8-benzyl-9-hydroxy-5-(1-tertbutyldimethylsilyloxy-2-methylpropan-2-yl)-15,15-dimethyl-3,6,13-trioxo-11-(4-(pyridin-2-yl)benzyl)-2-oxa-4,7,11,12-tetraazahexadecan-14-yl)carbamic acid trideuteromethyl ester 
• 1415634-39-7 ((5S,8S,9S,14S)-8-benzyl-9-hydroxy-5-(1-hydroxy-2-methylpropan-2-yl)-15,15-dimethyl-3,6,13-trioxo-11-(4-(pyridin-2-yl)benzyl)-2-oxa-4,7,11,12-tetraazahexadecan-14-yl)carbamic acid trideuteromethyl ester 

Relevant articles and documents

ATAZANAVIR METABOLITE DERIVATIVES

The present invention provides a compound of Formula (I) or (II) or a pharmaceutically acceptable salt of any of the foregoing, wherein each of the variables is as defined herein. The compounds of the invention can be used in therapy, for example, to improve the efficacy of a therapeutic agent that is either (i) metabolized by a liver metabolic enzyme; (ii) transported by an efflux pump; or (iii) a combination of (i) and (ii), especially a HCV protease inhibitor or a HIV protease inhibitor.