1416134-58-1

Basic information

• Product Name: ethyl (S)-2-((tert-butoxycarbonyl)amino)-6-(dimethyl(oxo)-λ⁶-sulfanylidene)-5-oxohexanoate
• Synonyms: ethyl (S)-2-((tert-butoxycarbonyl)amino)-6-(dimethyl(oxo)-λ⁶-sulfanylidene)-5-oxohexanoate
• CAS NO: 1416134-58-1
• Molecular Weight: 349.448
• Mol File: 1416134-58-1.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: ethyl (S)-2-((tert-butoxycarbonyl)amino)-6-(dimethyl(oxo)-λ⁶-sulfanylidene)-5-oxohexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (S)-2-((tert-butoxycarbonyl)amino)-6-(dimethyl(oxo)-λ⁶-sulfanylidene)-5-oxohexanoate(1416134-58-1)
• EPA Substance Registry System: ethyl (S)-2-((tert-butoxycarbonyl)amino)-6-(dimethyl(oxo)-λ⁶-sulfanylidene)-5-oxohexanoate(1416134-58-1)

Safety Data

• Hazardous Substances Data: 1416134-58-1(Hazardous Substances Data)

Upstream product

• 67-68-5 dimethyl sulfoxide 
• 144978-35-8 (S)-ethyl N-tert-butoxycarbonylpyroglutamate 
• 1774-47-6 trimethylsulfoxonium iodide 

Downstream Products

• 1416134-59-2 C₂₀H₂₉ClN₂O₅ 
• 1192500-31-4 (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicylco[3.2.1]octan-6-yl hydrogensulfate 
• 1192651-49-2 (1R,2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide 
• 1192491-61-4 (2S,5R)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide 7-oxo-6-(sulfoxy)monosodium salt 
• 1416134-49-0 (2S,5R)-5-(benzyloxyamino)-piperidine-2-carboxylic acid amide 
• 1192651-80-1 ({[(2S,5R)-2-carbamoyl-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3,2,1]-oct-6-yl]oxy}sulfonyl)tetrabutylammonium salt 
• 1416134-48-9 ethyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate oxalic acid salt 
• 1416134-60-5 5-benzyloxyiminopiperidine-2S-carboxylic acid ethyl ester 
• 1416134-63-8 (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octan-2-carboxylic acid ethyl ester 
• 1416134-47-8 C₁₅H₂₂N₂O₃ 
• 1487347-86-3 (2S,5S)-N-tert-butoxycarbonyl-5-hydroxy-2-carboxylic acid piperidine 

Relevant articles and documents

Synthesis method of ethyl (2S, 5R)-5-[(benzyloxy)amino]-piperidine-2-carboxylate

The invention discloses a synthesis method of ethyl (2S, 5R)-5-[(benzyloxy)amino]-piperidine-2-carboxylate. The method comprises the following steps: Boc-L-pyroglutamic acid ethyl ester used as an initial raw material and trimethylsulfoxonium iodide under

Preparation method of avibactam sodium intermediate

The invention provides a preparation method of an avibactam sodium intermediate, comprising: subjecting compound 1 to ring opening under alkaline conditions to obtain compound 2; subjecting the compound 2 to carbonyl conversion to obtain compound 3; subjecting the compound 3 to ring closing to obtain compound 4; removing t-butyloxycarboryl protective groups to obtain compound 5; allowing the compound 5 to react with oxalic acid to obtain (2S)-ethyl-5-((benzyloxy)amino)-piperidino-2-carbonate oxalate, compound 6. Reaction formula III is shown in the description. The preparation method is applicable to industrial production and has great application value.

CRYSTALLINE FORM OF A BETA-LACTAMASE INHIBITOR

This disclosure provides compositions containing solid forms of sodium (2S,5R)-2-(1,3,4-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate, and methods of manufacturing and using these compositions.