1416134-74-1

Basic information

• Product Name: methyl (2S,5R)-5-benzyloxyaminopiperidine-2-carboxylate oxalate
• Synonyms: methyl (2S,5R)-5-benzyloxyaminopiperidine-2-carboxylate oxalate
• CAS NO: 1416134-74-1
• Molecular Weight: 354.36
• Mol File: 1416134-74-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (2S,5R)-5-benzyloxyaminopiperidine-2-carboxylate oxalate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2S,5R)-5-benzyloxyaminopiperidine-2-carboxylate oxalate(1416134-74-1)
• EPA Substance Registry System: methyl (2S,5R)-5-benzyloxyaminopiperidine-2-carboxylate oxalate(1416134-74-1)

Safety Data

• Hazardous Substances Data: 1416134-74-1(Hazardous Substances Data)

Upstream product

• 144-62-7 oxalic acid 

Downstream Products

• 1416134-73-0 (2S,5R)-5-((benzyloxy)amino)piperidine-2-carboxylate methyl ester 
• 1192651-80-1 ({[(2S,5R)-2-carbamoyl-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3,2,1]-oct-6-yl]oxy}sulfonyl)tetrabutylammonium salt 
• 1416134-49-0 (2S,5R)-5-(benzyloxyamino)-piperidine-2-carboxylic acid amide 
• 1192491-61-4 (2S,5R)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide 7-oxo-6-(sulfoxy)monosodium salt 
• 1192651-49-2 (1R,2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide 
• 1192500-31-4 (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicylco[3.2.1]octan-6-yl hydrogensulfate 

Relevant articles and documents

A method of recovering and utilizing avibactam intermediate production waste liquid

The invention relates to a method of recovering and utilizing avibactam intermediate production waste liquid. The waste liquid produced in a production process of an avibactam intermediate that is 5R-benzyloxyaminopiperidine-2S-formateoxalate IIb is adopted as an initial raw material, and is oxidized to generate 5R-benzyloxyiminopiperidine-2S-formate III; the compound III is subjected to selectivereduction, chiral crystallization resolution and filtration to obtain the solid 5R-benzyloxyaminopiperidine-2S-formateoxalateoxalate IIb; and the obtained filtrate is subjected to the oxidation, reduction and resolution steps again. The compound IIb is neutralized to prepare 5R-benzyloxyaminopiperidine-2S-formate IIa, and the compound IIa or the compound IIb can be utilized to prepare avibactam I. The method is simple and convenient to operate, the atom utilization rate is increased, and the total yield of the compound IIb can be 99.0% or above, thus facilitating cost reduction, facilitatingreduction of avibactam waste liquid and facilitating environment protection.