1416159-63-1

Basic information

• Product Name: N-[4-[2-(2,4-diamino-5-tosyl-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-ylmethyl) methylamino]benzoyl]-L-glutamatic acid
• Synonyms: N-[4-[2-(2,4-diamino-5-tosyl-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-ylmethyl) methylamino]benzoyl]-L-glutamatic acid
• CAS NO: 1416159-63-1
• Molecular Weight: 611.679
• Mol File: 1416159-63-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[4-[2-(2,4-diamino-5-tosyl-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-ylmethyl) methylamino]benzoyl]-L-glutamatic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-[4-[2-(2,4-diamino-5-tosyl-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-ylmethyl) methylamino]benzoyl]-L-glutamatic acid(1416159-63-1)
• EPA Substance Registry System: N-[4-[2-(2,4-diamino-5-tosyl-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-ylmethyl) methylamino]benzoyl]-L-glutamatic acid(1416159-63-1)

Safety Data

• Hazardous Substances Data: 1416159-63-1(Hazardous Substances Data)

Upstream product

• 76822-61-2 2,4-Diamino-6-(hydroxymethyl)pyrido<3,2-d>pyrimidine 
• 76807-55-1 6-(Acetoxymethyl)-2,4-dichloropyrido<3,2-d>pyrimidine 
• 76807-54-0 6-(Acetoxymethyl)-2,4-dioxopyrido<3,2-d>pyrimidine 
• 1416159-59-5 diethyl N-[4-[2-(2,4-diamino-5-tosyl-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-ylmethyl) methylamino]benzoyl]-L-glutamate 
• 1383672-71-6 diethyl N-[4-[2-(2,4-diamino-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-ylmethyl) methylamino]benzoyl]-L-glutamate 
• 76807-60-8 diethyl N-[4-[(2,4-diaminopyrido[3,2-d]pyrimidin-6-ylmethyl)methylamino]benzoyl]-L-glutamate 
• 2378-95-2 diethyl N-<4-(methylamino)benzoyl>-L-glutamate 

Relevant articles and documents

Mechanism-based design, synthesis and biological studies of N 5-substituted tetrahydrofolate analogs as inhibitors of cobalamin-dependent methionine synthase and potential anticancer agents

A number of 8-deazatetrahydrofolates bearing electrophilic groups on N 5 were designed and synthesized based on the action mechanism of methionine synthase, and their biological activities were investigated as well. Compounds (11b, 12b and 16)