1416914-85-6

Basic information

• Product Name: 1-(4-(6-(dimethylamino)pyridin-3-yl)benzyl)-3-methoxypyridin-2-one
• Synonyms: 1-(4-(6-(dimethylamino)pyridin-3-yl)benzyl)-3-methoxypyridin-2-one
• CAS NO: 1416914-85-6
• Molecular Weight: 335.406
• Mol File: 1416914-85-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-(6-(dimethylamino)pyridin-3-yl)benzyl)-3-methoxypyridin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(6-(dimethylamino)pyridin-3-yl)benzyl)-3-methoxypyridin-2-one(1416914-85-6)
• EPA Substance Registry System: 1-(4-(6-(dimethylamino)pyridin-3-yl)benzyl)-3-methoxypyridin-2-one(1416914-85-6)

Safety Data

• Hazardous Substances Data: 1416914-85-6(Hazardous Substances Data)

Upstream product

• 1416914-77-6 1-(4-bromobenzyl)-3-methoxypyridin-2(1H)-one 
• 579525-46-5 6-(dimethylamino)pyridin-3-ylboronic acid 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 20928-63-6 3-methoxy-1H-pyridin-2-one 

Downstream Products

• 1416914-94-7 1-(4-(6-(dimethylamino)pyridin-3-yl)benzyl)-3-methoxypyridin-2-thione 
• 1416915-03-1 1-(4-(6-(dimethylamino)pyridin-3-yl)benzyl)-3-hydroxypyridin-2-one 
• 1416915-13-3 C₁₉H₁₉N₃OS 

Relevant articles and documents

3-Hydroxypyridin-2-thione as Novel Zinc Binding Group for Selective Histone Deacetylase Inhibition

Small molecules bearing hydroxamic acid as the zinc binding group (ZBG) have been the most effective histone deacetylase inhibitors (HDACi) to date. However, concerns about the pharmacokinetic liabilities of the hydroxamic acid moiety have stimulated rese