1417160-79-2Relevant articles and documents
A new highly versatile handle for chemistry on a solid support: The pipecolic linker
Masurier, Nicolas,Verdie, Pascal,Amblard, Muriel,Martinez, Jean,Subra, Gilles,Zajdel, Pawel,Pawalowski, MacIej
, p. 11536 - 11540,5 (2012/12/12)
The versatility of the pipecolic linker (Pip-linker) is illustrated by the synthesis of modified amino acids, C-terminal-modified pseudopeptides, and cyclic peptides, through side-chain anchoring of a lysine residue (see figure). Introduction of the first residue was easily accomplished and the Pip-linker revealed to be robust enough to support various chemical modifications. Copyright