1417526-67-0

Basic information

• Product Name: 4-ethyl-5-(4'-(trifluoromethyl)biphenyl-4-yl)-4H-1,2,4-triazole-3-thiol
• Synonyms: 4-ethyl-5-(4'-(trifluoromethyl)biphenyl-4-yl)-4H-1,2,4-triazole-3-thiol
• CAS NO: 1417526-67-0
• Molecular Weight: 349.379
• Mol File: 1417526-67-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-ethyl-5-(4'-(trifluoromethyl)biphenyl-4-yl)-4H-1,2,4-triazole-3-thiol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ethyl-5-(4'-(trifluoromethyl)biphenyl-4-yl)-4H-1,2,4-triazole-3-thiol(1417526-67-0)
• EPA Substance Registry System: 4-ethyl-5-(4'-(trifluoromethyl)biphenyl-4-yl)-4H-1,2,4-triazole-3-thiol(1417526-67-0)

Safety Data

• Hazardous Substances Data: 1417526-67-0(Hazardous Substances Data)

Upstream product

• 195457-71-7 4-[4-(trifluoromethyl)phenyl]benzoic acid 
• 127783-73-7 methyl 4’-(trifluoromethyl)-[1,1’-biphenyl]-4-carboxylate 
• 542-85-8 Ethyl isothiocyanate 
• 1417526-66-9 4'-(trifluoromethyl)biphenyl-4-carbohydrazide 

Downstream Products

• 1417526-68-1 4-ethyl-3-(4'-(trifluoromethyl)biphenyl-4-yl)-4H-1,2,4-triazole 
• 1417526-69-2 (4-ethyl-5-(4'-(trifluoromethyl)biphenyl-4-yl)-4H-1,2,4-triazol-3-yl)methanol 
• 1417526-70-5 3-(azido methyl)-4-ethyl-5-(4'-(trifluoromethyl)biphenyl-4-yl)-4H-1,2,4-triazole 
• 1417526-71-6 (4-ethyl-5-(4'-(trifluoromethyl)biphenyl-4-yl)-4H-1,2,4-triazol-3-yl)methanamine 
• 1417526-73-8 1-((4-ethyl-5-(4'-(trifluoromethyl)biphenyl-4-yl)-4H-1,2,4-triazol-3-yl)methyl)-2-thioxo-2,3,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4(5H)-one 
• 1417527-29-7 1-((4-ethyl-5-(4'-(trifluoromethyl)biphenyl-4-yl)-4H-1,2,4-triazol-3-yl)methyl)-2-(4-fluorobenzylthio)-6,7-dihydro-1H-cyclopenta[d]pyrimidin-4(5H)-one 
• 1417527-30-0 1-((4-ethyl-5-(4'-(trifluoromethyl)biphenyl-4-yl)-4H-1,2,4-triazol-3-yl)methyl)-2-(4-methoxybenzylthio)-6,7-dihydro-1H-cyclopenta[d]pyrimidin-4(5H)-one 

Relevant articles and documents

AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE

The present invention relates to the field of pharmaceutical chemistry, and in particular, to a novel class of azole compounds represented by general formula (I), (II) or (III) and a preparation method thereof, a pharmaceutical composition with the compounds as active components, and a use of the azole compounds and the pharmaceutical composition in the preparation of a medicament for treatment of diseases associated with Lp-PLA2 enzyme activities, wherein each substituent is as defined in the specification.