1417600-63-5

Basic information

• Product Name: N-(diphenylmethylene)pent-4-yn-1-amine
• CAS NO: 1417600-63-5
• Molecular Weight: 247.34
• Mol File: 1417600-63-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(diphenylmethylene)pent-4-yn-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(diphenylmethylene)pent-4-yn-1-amine(1417600-63-5)
• EPA Substance Registry System: N-(diphenylmethylene)pent-4-yn-1-amine(1417600-63-5)

Safety Data

• Hazardous Substances Data: 1417600-63-5(Hazardous Substances Data)

Upstream product

• 1013-88-3 Benzophenone imine 
• 15252-44-5 1-amino-pent-4-yne 
• 6097-07-0 N-(pent-4-ynyl)phthalimide 
• 14267-92-6 1-chloro-4-pentyne 

Downstream Products

• 1417600-62-4 C₃₀H₄₅NSn 
• 38759-59-0 N⁽¹⁾-benzhydryl-2-pyrrolidinone 
• 1417600-61-3 (2E,4S,5S,8E)-ethyl 8-(1-benzhydrylpyrrolidin-2-ylidene)-4-((tert-butyldimethylsilyl)oxy)-5-methyl-7-oxooct-2-enoate 

Relevant articles and documents

Total synthesis of the lycopodium alkaloid serratezomine a using free radical-mediated vinyl amination to prepare a β-stannyl enamine linchpin

Serratezomine A is a member of the structurally diverse class of compounds known as the Lycopodium alkaloids. The key supporting studies and successful total synthesis of serratezomine A are described in this account. Significant features of the synthesis include the first application of free radical mediated vinyl amination and Hwu's oxidative allylation in a total synthesis and an intramolecular lactonization via a transannular SNi reaction. Minimal use of protecting groups and the highly diastereoselective formation of a hindered, quaternary stereocenter using an umpolung allylation are also highlights from a strategy perspective. Observation of quaternary carbon epimerization via a retro-Mannich/Mannich sequence highlights the additional challenge presented by the axial alcohol at C8 in serratezomine A.