1417736-32-3

Basic information

• Product Name: (4-{4-amino-7-[2-(aminomethyl)-1,3-thiazol-4-yl]pyrrolo[2,1-f][1,2,4]triazin-5-yl}-2,6-difluorophenyl)methanol
• Synonyms: (4-{4-amino-7-[2-(aminomethyl)-1,3-thiazol-4-yl]pyrrolo[2,1-f][1,2,4]triazin-5-yl}-2,6-difluorophenyl)methanol
• CAS NO: 1417736-32-3
• Molecular Weight: 388.401
• Mol File: 1417736-32-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-{4-amino-7-[2-(aminomethyl)-1,3-thiazol-4-yl]pyrrolo[2,1-f][1,2,4]triazin-5-yl}-2,6-difluorophenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-{4-amino-7-[2-(aminomethyl)-1,3-thiazol-4-yl]pyrrolo[2,1-f][1,2,4]triazin-5-yl}-2,6-difluorophenyl)methanol(1417736-32-3)
• EPA Substance Registry System: (4-{4-amino-7-[2-(aminomethyl)-1,3-thiazol-4-yl]pyrrolo[2,1-f][1,2,4]triazin-5-yl}-2,6-difluorophenyl)methanol(1417736-32-3)

Safety Data

• Hazardous Substances Data: 1417736-32-3(Hazardous Substances Data)

Upstream product

• 937047-27-3 1-(4-amino-5-bromopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2-chloroethanone 
• 162744-59-4 (4-bromo-2,6-difluoro-phenyl)methanol 
• 1417736-43-6 [2,6-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol 
• 1417736-88-9 tert-butyl {[4-(4-amino-5-bromopyrrolo[2,1-f][1,2,4]triazin-7-yl)-1,3-thiazol-2-yl]methyl}carbamate 

Relevant articles and documents

HYDROXYMETHYLARYL-SUBSTITUTED PYRROLOTRIAZINES AS ALK1 INHIBITORS

This invention relates to novel 5-[(hydroxymethyl)aryl] -substituted pyrrolo[2, 1-f][1, 2, 4] triazin-4-amines of formula (I), to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating angiogenesis-related disorders, in particular angiogenesis-related ocular disorders.