14178-44-0

Basic information

• Product Name: 4-Pyridinecarboxamide, N-phenyl-, 1-oxide
• CAS NO: 14178-44-0
• Molecular Formula: C12H10N2O2
• Molecular Weight: 214.224
• Mol File: 14178-44-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-Pyridinecarboxamide, N-phenyl-, 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinecarboxamide, N-phenyl-, 1-oxide(14178-44-0)
• EPA Substance Registry System: 4-Pyridinecarboxamide, N-phenyl-, 1-oxide(14178-44-0)

Safety Data

• Hazardous Substances Data: 14178-44-0(Hazardous Substances Data)

Upstream product

• 14254-57-0 4-(chlorocarbonyl)pyridine 
• 55-22-1 pyridine-4-carboxylic acid 
• 3034-31-9 N-phenylisonicotinamide 

Downstream Products

• 126798-26-3 4-methoxy-3-(p-methoxyphenyl)-furo<3,4-c>pyridine-1(3H)-one 
• 126798-31-0 3-(p-methoxyphenyl)-furo<3,4-c>pyridine-1,4(3H,5H)-dione 
• 126798-21-8 2-methoxy-N-phenylisonicotinamide 
• 80194-83-8 2-chloro-N-phenylisonicotinamide 

Relevant articles and documents

HIV protease inhibitors

HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.

Intermediate and process for making

The present invention provides novel HIV protease inhibitors, pharmaceutical formulations containing those compounds and methods of treating and/or preventing HIV infection and/or AIDS.