1417917-59-9

Basic information

• Product Name: 2-chloromethyl-3,5,7,8-tetrahydro-pyrano[4,3-d]pyrimidin-4-one
• Synonyms: 2-chloromethyl-3,5,7,8-tetrahydro-pyrano[4,3-d]pyrimidin-4-one
• CAS NO: 1417917-59-9
• Molecular Weight: 200.625
• Mol File: 1417917-59-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-chloromethyl-3,5,7,8-tetrahydro-pyrano[4,3-d]pyrimidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloromethyl-3,5,7,8-tetrahydro-pyrano[4,3-d]pyrimidin-4-one(1417917-59-9)
• EPA Substance Registry System: 2-chloromethyl-3,5,7,8-tetrahydro-pyrano[4,3-d]pyrimidin-4-one(1417917-59-9)

Safety Data

• Hazardous Substances Data: 1417917-59-9(Hazardous Substances Data)

Upstream product

• 29943-42-8 Tetrahydro-4H-pyran-4-one 
• 127956-11-0 4-oxotetrahydro-2H-pyran-3-carboxylic acid methyl ester 
• 20846-52-0 2-chloro-acetamidine 

Downstream Products

• 1417917-24-8 C₂₅H₃₀N₄O₅ 
• 1417917-22-6 C₂₅H₃₀N₄O₅ 
• 1417917-38-4 C₂₆H₃₂N₄O₅ 
• 1417917-39-5 C₂₆H₃₂N₄O₅ 
• 1417917-40-8 C₂₆H₃₂N₄O₅ 
• 1417917-23-7 2-{(R)-3-[4-(4-Methoxy-benzoyl)-piperidin-1-yl]-2-oxo-pyrrolidin-1-ylmethyl}-3,5,7,8-tetrahydro-pyrano[4,3-d]pyrimidin-4-one 
• 1417917-33-9 C₂₆H₃₂N₄O₅ 
• 1417917-34-0 C₂₆H₃₂N₄O₅ 
• 1417917-30-6 C₂₄H₂₇FN₄O₄ 
• 1417917-31-7 C₂₄H₂₇FN₄O₄ 
• 1417917-32-8 2-{(R)-3-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-2-oxo-pyrrolidin-1-ylmethyl}-3,5,7,8-tetrahydro-pyrano[4,3-d]pyrimidin-4-one 
• 1417917-29-3 2-{3-[4-(4-Chloro-benzoyl)-piperidin-1-yl]-2-oxo-pyrrolidin-1-ylmethyl}-3,5,7,8-tetrahydro-pyrano[4,3-d]pyrimidin-4-one 
• 1419955-07-9 2-((benzylamino)methyl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one 
• 1419949-88-4 2-(4-(4-fluorobenzoyl)piperidin-1-yl)-N-((4-oxo-4,5,7,8-tetrahydro-3H-pyrano[4,3-d]pyrimidin-2-yl)methyl)-N-(pyridin-2-ylmethyl)acetamide 

Relevant articles and documents

4 - PIPERIDINYL COMPOUNDS FOR USE AS TANKYRASE INHIBITORS

The present invention provides for compounds of formula (I).The present invention also provides for pharmaceutical compositions and combinations comprising a compound of formula (I) as well as for the use of such compounds as tankyrase inhibitors and in the treatment of Wnt signaling and tankyrase 1 and 2 signaling related disorders which include, but are not limited to, cancer.

NOVEL 2-PIPERIDIN-1-YL-ACETAMIDE COMPOUNDS FOR USE AS TANKYRASE INHIBITORS

The present invention provides for compounds of formula (I), wherein R1-R5 and L are defined herein. The present invention also provides for pharmaceutical compositions and combinations comprising a compound of formula (I) as well as for the use of such compounds as tankyrase inhibitors and in the treatment of Wnt signaling and tankyrase 1 and 2 signaling related disorders which include, but are not limited to, cancer.