1417919-67-5

Basic information

• Product Name: 2-(4'-fluoro-[1,1'-biphenyl]-4-yl)-4H-chromen-4-one
• Synonyms: 2-(4'-fluoro-[1,1'-biphenyl]-4-yl)-4H-chromen-4-one
• CAS NO: 1417919-67-5
• Molecular Weight: 316.331
• Mol File: 1417919-67-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4'-fluoro-[1,1'-biphenyl]-4-yl)-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4'-fluoro-[1,1'-biphenyl]-4-yl)-4H-chromen-4-one(1417919-67-5)
• EPA Substance Registry System: 2-(4'-fluoro-[1,1'-biphenyl]-4-yl)-4H-chromen-4-one(1417919-67-5)

Safety Data

• Hazardous Substances Data: 1417919-67-5(Hazardous Substances Data)

Upstream product

• 1765-93-1 4-fluoroboronic acid 
• 132351-68-9 3-(4-bromophenyl)-4H-1-benzopyran-4-one 
• 108-95-2 phenol 
• 122-79-2 Phenyl acetate 
• 118-93-4 o-hydroxyacetophenone 
• 36695-16-6 2-(4-bromobenzoyloxy)acetophenone 
• 20525-20-6 4'-bromoflavone 

Relevant articles and documents

Flavones as isosteres of 4(1H)-quinolones: Discovery of ligand efficient and dual stage antimalarial lead compounds

Malaria is responsible for nearly one million deaths annually, and the increasing prevalence of multi-resistant strains of Plasmodium falciparum poses a great challenge to controlling the disease. A diverse set of flavones, isosteric to 4(1H)-quinolones, were prepared and profiled for their antiplasmodial activity against the blood stage of P. falciparum W2 strain, and the liver stage of the rodent parasite Plasmodium berghei. Ligand efficient leads were identified as dual stage antimalarials, suggesting that scaffold optimization may afford potent antiplasmodial compounds.