1418142-88-7

Basic information

• Product Name: 4-((3-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl)amino)cyclohexanone
• Synonyms: 4-((3-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl)amino)cyclohexanone
• CAS NO: 1418142-88-7
• Molecular Weight: 340.812
• Mol File: 1418142-88-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-((3-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl)amino)cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((3-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl)amino)cyclohexanone(1418142-88-7)
• EPA Substance Registry System: 4-((3-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl)amino)cyclohexanone(1418142-88-7)

Safety Data

• Hazardous Substances Data: 1418142-88-7(Hazardous Substances Data)

Upstream product

• 87976-86-1 4‐aminocyclohexanone 
• 1111106-54-7 3-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5(4H)-one 
• 95750-97-3 4-(3-chlorophenyl)-1H-pyrazol-5-amine 
• 62739-01-9 3-(dimethylamino)-2-(3-chlorophenyl)acrylonitrile 
• 1529-41-5 3-chloro-benzeneacetonitrile 

Relevant articles and documents

Substituted imidazo[1,2-b]pyridazines as protein kinase inhibitors

The present invention provides protein kinase having one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.

HETEROCYCLIC PROTEIN KINASE INHIBITORS

The present invention provides protein kinase having one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.