14182-01-5Relevant articles and documents
Novel one-pot approach to synthesis of indanones Through Sb(V)-catalyzed reaction of phenylalkynes with aldehydes
Saito, Akio,Umakoshi, Masaharu,Yagyu, Naomi,Hanzawa, Yuji
, p. 1783 - 1785 (2008)
Catalytic SbF5 and the use of EtOH as an additive efficiently converted a mixture of phenylalkynes and aldehydes to indanone compounds in one pot, and the reaction stereoselectively afforded the corresponding 2,3-disubstituted indanones as a single trans-isomer.
Crossing extreme mechanistic barriers by antibody catalysis: Syn elimination to a cis olefin
Cravatt, Benjamin F.,Ashley, Jon A.,Janda, Kim D.,Boger, Dale L.,Lerner, Richard A.
, p. 6013 - 6014 (1994)
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Palladium-Catalyzed Carbonylative Synthesis of α-Branched Enones from Aryl Iodides and Arylallenes
Geng, Hui-Qing,Hou, Chen-Yang,Wang, Le-Cheng,Wu, Xiao-Feng
, p. 1160 - 1163 (2020)
In this communication, an interesting carbonylation protocol for the preparation of α-branched enones has been established. Starting from readily available aryl iodides and allenes, with formic acid as the CO source and reductant, moderate to good yields of the desired enones were isolated. Although it is a carbonylation methodology, the use of a CO source can avoid the manipulation of CO gas directly. Notably, this procedure also presents the first example on carbonylative synthesis of α-branched enones.
Palladium-Catalyzed Synthesis of α-Methyl Ketones from Allylic Alcohols and Methanol
Biswal, Priyabrata,Samser, Shaikh,Meher, Sushanta Kumar,Chandrasekhar, Vadapalli,Venkatasubbaiah, Krishnan
supporting information, p. 413 - 419 (2021/11/01)
One-pot synthesis of α-methyl ketones starting from 1,3-diaryl propenols or 1-aryl propenols and methanol as a C1 source is demonstrated. This one-pot isomerization-methylation is catalyzed by commercially available Pd(OAc)2 with H2O as the only by-product. Mechanistic studies and deuterium labelling experiments indicate the involvement of isomerization of allyl alcohol followed by methylation through a hydrogen-borrowing pathway in these isomerization-methylation reactions.
Substituent-Controlled Divergent Cascade Cycloaddition Reactions of Chalcones and Arylalkynols: Access to Spiroketals and Oxa-Bridged Fused Heterocycles
Chang, Weixing,Kong, Jingyang,Li, Jing,Liu, Lingyan,Wang, Hongkai,Zeng, Tianlong
supporting information, p. 4024 - 4032 (2021/07/12)
Herein, we report substituent-controlled divergent cascade cycloaddition reactions of chalcones and arylalkynols in the presence of PtI2. Depending on the substituent on the chalcone, either spiroketals or oxa-bridged fused heterocycles could be obtained in the ranges of 86–97% and 87–95% yields under identical reaction conditions. Control experiments were carried out to elucidate the origin of the high chemoselectivity. These provide a method for the synthesis of a diverse array of structurally complex oxygen-containing heterocycles. (Figure presented.).
New photochromic α-methylchalcones are highly photostable, even under singlet oxygen conditions: Breaking the α-methyl michael-system reactivity by reversible peroxybiradical formation
?ngel, Banu,Brüllingen, Eric,Griesbeck, Axel G.,Renner, Melissa
, (2021/06/14)
The α-methylated chalcones 7a–7e behave as P-type photochromic substances with photo-stationary states (PSS) as high as 15:85 when irradiated at 350 nm. These compounds are easily accessible in pure E-configuration by aldol condensation or by oxidative co
