1418224-47-1

Basic information

• Product Name: (Z)-4-(4-nitrophenyl)-2-p-tolylbut-2-en-1-ol
• Synonyms: (Z)-4-(4-nitrophenyl)-2-p-tolylbut-2-en-1-ol
• CAS NO: 1418224-47-1
• Molecular Weight: 283.327
• Mol File: 1418224-47-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-4-(4-nitrophenyl)-2-p-tolylbut-2-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-4-(4-nitrophenyl)-2-p-tolylbut-2-en-1-ol(1418224-47-1)
• EPA Substance Registry System: (Z)-4-(4-nitrophenyl)-2-p-tolylbut-2-en-1-ol(1418224-47-1)

Safety Data

• Hazardous Substances Data: 1418224-47-1(Hazardous Substances Data)

Upstream product

• 1379820-13-9 4-p-methylphenyl-1,2-oxaborol-2(5H)-ol 
• 100-11-8 1-bromomethyl-4-nitro-benzene 

Relevant articles and documents

A new synthetic method of (Z)-4-aryl-but-2-en-1-ols via Suzuki-Miyaura cross-coupling reaction of 4-substituted 1,2-oxaborol-2(5H)-ols with benzyl bromides

Z and E configuration 4-aryl-but-2-en-1-ols were isolated from several terrestrial plants, and (Z)-4-aryl-but-2en-1-ols were found to have choleretic activity. Strategies have been reported to synthesize (E)-4-aryl-but-2-en-1ols with high selectivity. However, there is no method to obtain (Z)-4-aryl-but-2-en-1-ols with high selectivity now. We developed a Suzuki-Miyaura cross-coupling reaction of 1,2-oxaborol-2(5H)-ols with benzyl bromides to synthesize (Z)-4-aryl-but-2-en-1-ols, the products were obtained in up to 94% isolated yield. Copyright