1418307-17-1 Usage
Description
1-Pyrrolidinecarboxylic acid, 2-[[[(3-chloro-2-pyrazinyl)methyl]amino]carbonyl]-, phenylmethyl ester, (2S)is a complex ester derivative of 1-Pyrrolidinecarboxylic acid with a phenylmethyl ester group and a pyrazinylmethylamino carbonyl moiety. 1-Pyrrolidinecarboxylic acid, 2-[[[(3-chloro-2-pyrazinyl)methyl]amino]carbonyl]-, phenylmethyl ester, (2S)exhibits stereochemistry in its (2S)-stereoisomeric form, which is significant for its potential biological activities and applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
1-Pyrrolidinecarboxylic acid, 2-[[[(3-chloro-2-pyrazinyl)methyl]amino]carbonyl]-, phenylmethyl ester, (2S)is used as a building block for the synthesis of pharmacologically active compounds due to its unique chemical structure and potential for diverse biological activities.
Used in Drug Development:
1-Pyrrolidinecarboxylic acid, 2-[[[(3-chloro-2-pyrazinyl)methyl]amino]carbonyl]-, phenylmethyl ester, (2S)is utilized in drug development for its potential to contribute to the creation of new therapeutic agents, given its specific structural features that may interact with biological targets in novel ways.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1-Pyrrolidinecarboxylic acid, 2-[[[(3-chloro-2-pyrazinyl)methyl]amino]carbonyl]-, phenylmethyl ester, (2S)serves as a valuable research tool for understanding the structure-activity relationships of potential drug candidates and for optimizing their pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1418307-17-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,1,8,3,0 and 7 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1418307-17:
(9*1)+(8*4)+(7*1)+(6*8)+(5*3)+(4*0)+(3*7)+(2*1)+(1*7)=141
141 % 10 = 1
So 1418307-17-1 is a valid CAS Registry Number.
1418307-17-1Relevant articles and documents
PROCESSES FOR THE PREPARATION OF 4-{8-AMINO-3-[(2S)-1-(BUT-2-YNOYL)-PYRROLIDIN-2-YL]IMIDAZO[1,5-A]-PYRAZIN-1-YL}N-(PYRIDIN-2-YL)-BENZAMIDE
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, (2020/03/23)
The present disclosure relates, in general, to improved processes for the preparation of 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)-benzamide, particularly large-scale processes for manufacturing 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide and intermediates used in such processes.
IMIDAZOPYRIDINAMINE PHENYL DERIVATIVE AND USE THEREOF
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Paragraph 0038, (2019/05/16)
The present invention relates to imidazopyridinamine phenyl derivatives, pharmaceutically acceptable salts and hydrates thereof, or metabolites thereof formed by any form of metabolism, and uses thereof in the preparation of medicaments for preventing and
A Manufacturing Process to an Intermediate in the Synthesis of Acalabrutinib
Chen, Bo,Golden, Michael,Li, Zhonglian,Xu, Liwen,Xu, Zhaofu,Yao, Xiaolong
, p. 1458 - 1460 (2018/10/15)
Optimization and application of the reported synthesis of (3-chloropyrazin-2-yl)methanamine 3 have provided a high yielding, fully telescoped procedure to key intermediate 5 in the synthesis of acalabrutinib.
