141836-50-2 Usage
Description
[4-(tert-Butyldimethylsilyloxymethyl)cyclohexyl]methanol is a colorless oil with unique chemical properties that make it a valuable intermediate in the synthesis of various compounds. Its structure features a cyclohexyl group with a tert-butyldimethylsilyloxymethyl moiety attached to the 4-position, and a hydroxymethyl group at the 1-position.
Uses
Used in Pharmaceutical Industry:
[4-(tert-Butyldimethylsilyloxymethyl)cyclohexyl]methanol is used as an intermediate in the production of Rho kinase inhibitors for the pharmaceutical industry. Rho kinase inhibitors are important in the treatment of various diseases, including cardiovascular and neurological disorders, by modulating the activity of Rho-associated protein kinase.
Used in Neurochemistry Research:
In the field of neurochemistry, [4-(tert-Butyldimethylsilyloxymethyl)cyclohexyl]methanol is used as an intermediate for the synthesis of neurite outgrowth promoters. These compounds play a crucial role in the development and maintenance of the nervous system, as they help in the growth and extension of nerve cells, which is essential for proper neuronal function and communication.
Used in Chemical Synthesis:
As a colorless oil with specific functional groups, [4-(tert-Butyldimethylsilyloxymethyl)cyclohexyl]methanol can also be utilized in various chemical synthesis processes across different industries. Its unique structure allows it to serve as a versatile building block for creating a wide range of compounds with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 141836-50-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,8,3 and 6 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 141836-50:
(8*1)+(7*4)+(6*1)+(5*8)+(4*3)+(3*6)+(2*5)+(1*0)=122
122 % 10 = 2
So 141836-50-2 is a valid CAS Registry Number.
141836-50-2Relevant articles and documents
NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF
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Paragraph 00201, (2021/11/13)
The invention provides compounds for inhibiting glucosylceramidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds.
IMIDAZOLE COMPOUND
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Paragraph 0112-0113; 0209-0210, (2018/03/25)
Disclosed is an imidazole compound, in particular, the compound as shown in formula (I) and a pharmaceutically acceptable salt or tautomer thereof are disclosed.
Facile cleavage of silyl protecting groups with catalytic amounts of FeCl3
Yang, Yong-Qing,Cui, Jia-Rong,Zhu, Lin-Gui,Sun, Ya-Ping,Wu, Yikang
, p. 1260 - 1262 (2007/10/03)
A very mild and environmentally benign method for removal of silyl protecting groups using catalytic amounts of iron ion in MeOH is presented. The method is particularly effective for cleaving triethylsilyl (TES) protecting groups. Georg Thieme Verlag Stuttgart.
