141857-33-2

Basic information

• Product Name: 2-Biphenyl-4-yl-3-hydroxy-3-(4-trifluoromethyl-phenyl)-propionic acid
• CAS NO: 141857-33-2
• Molecular Weight: 386.37
• Mol File: 141857-33-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Biphenyl-4-yl-3-hydroxy-3-(4-trifluoromethyl-phenyl)-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Biphenyl-4-yl-3-hydroxy-3-(4-trifluoromethyl-phenyl)-propionic acid(141857-33-2)
• EPA Substance Registry System: 2-Biphenyl-4-yl-3-hydroxy-3-(4-trifluoromethyl-phenyl)-propionic acid(141857-33-2)

Safety Data

• Hazardous Substances Data: 141857-33-2(Hazardous Substances Data)

Upstream product

• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 5728-52-9 (4-biphenylyl)acetic acid 

Downstream Products

• 141857-34-3 2-Biphenyl-4-yl-3-hydroxy-3-(4-trifluoromethyl-phenyl)-propionic acid methyl ester 
• 141857-34-3 2-Biphenyl-4-yl-3-hydroxy-3-(4-trifluoromethyl-phenyl)-propionic acid methyl ester 

Relevant articles and documents

Nonsteroidal antiinflammatory agents. Part 21: Optically active stereoisomers of p-trifluoromethylphenyl- and p-thioanisyl-biphenylyl-hydroxypropionic acids

The synthesis, diastereomeric separation, assignment to erythro- and threo-configuration by 1HNMR, and optical resolution of 3-(p-trifluoromethyl-phenyl)- and (p-thioanisyl)-2-biphenylyl-3-hydroxypropionic acids are described. The enantiomers were submitted to a preliminary assay to determine antiinflammatory activity.