141923-61-7Relevant articles and documents
Selective pivaloylation of hydroxyl groups by 3-Pivaloyl-1,3-thiazolidine-2-thione under neutral conditions
Yamada, Shinji
, p. 2171 - 2174 (1992)
Under neutral conditions, 3-pivaloyl-l,3-thiazolidine-2-thione (PTT) was found to act as a selective pivaloylating reagent for hydroxyl groups. The primary hydroxyl groups of diols containing primary and secondary hydroxyl groups, and the phenolic hydroxyl groups of the diols having alcoholic and phenolic hydroxyl groups were selectively pivaloylated by PTT.
COMPOUNDS WITH MIXED PDE-INHIBITORY AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITY FOR TREATMENT OF HEART FAILURE
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Page/Page column 44-45, (2010/11/08)
This invention provides compounds that possess inhibitory activity against β-adrenergic receptors and phosphodiesterases, including phosphodiesterase 3 (PDE3). This invention further provides pharmaceutical compositions comprising such compounds; methods