1419293-70-1

Basic information

• Product Name: 1,1,1-trifluoro-2-phenyl-3-(quinolin-2-yl)propan-2-ol
• Synonyms: 1,1,1-trifluoro-2-phenyl-3-(quinolin-2-yl)propan-2-ol
• CAS NO: 1419293-70-1
• Molecular Weight: 317.31
• Mol File: 1419293-70-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,1,1-trifluoro-2-phenyl-3-(quinolin-2-yl)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1-trifluoro-2-phenyl-3-(quinolin-2-yl)propan-2-ol(1419293-70-1)
• EPA Substance Registry System: 1,1,1-trifluoro-2-phenyl-3-(quinolin-2-yl)propan-2-ol(1419293-70-1)

Safety Data

• Hazardous Substances Data: 1419293-70-1(Hazardous Substances Data)

Upstream product

• 91-63-4 2-methylquinoline 
• 434-45-7 2,2,2-Trifluoroacetophenone 

Relevant articles and documents

Indium-catalyzed C(sp3)-H functionalization of 2-methylazaarenes through direct benzylic addition to trifluoromethyl ketones

The application of trivalent indium for the Lewis acid-catalyzed C(sp3)-H functionalization of 2-methylazaarenes is reported. InCl3 was discovered to catalyze the direct addition of the benzylic C-H bond in the azaarenes to trifluoro

Iron-catalyzed benzylic addition of 2-methyl azaarenes to substituted trifluoromethyl ketones

This paper demonstrated a new and economical methodology using Fe(ClO4)2·H2O as a catalyst for the direct C(sp3)–H functionalization of 2-methyl azaarenes via addition to trifluoromethyl ketones. The use of Fe salts as a Lewis acid catalyst has shown great potential as an accessible, affordable, and effective catalyst for the reaction. Under mild, optimized conditions, an extensive range of 2-alkenylated azaarenes was produced with yields of up to 95%.