141987-28-2Relevant articles and documents
Efficient synthesis of 8-methoxy-3,4-dihydro-2H-1-benzopyran-3-ol
Shindikar,Viswanathan
, p. 1141 - 1145 (2011/05/05)
The article reports a practical, simple, and inexpensive procedure for the synthesis of 8-methoxy-3,4-dihydro-2H-1-benzopyran-3-ol (1). 2-Methoxy phenol on treatment offers the oxirane compound, which undergoes ring cleavage under acidic conditions to give a chlorohydrin, which on acylation and cyclization in the presence of stannic chloride followed by hydrolysis of the acetyl group, yields the desired compound (1).