141996-62-5Relevant articles and documents
L-aspartic acid bis(trimethylsilyl) ester: A convenient starting material for the acylation of L-aspartic acid
Castano, Ana M.,Echavarren, Antonio M.
, p. 3377 - 3384 (2007/10/02)
Reaction of L-aspartic acid with excess of bis(trimethylsilyl)amine under reflux provides optically pure L-aspartic acid bis(trimethylsilyl) ester in quantitative yield. This silyl ester reacts with a variety of acylating reagens in tetrahydrofuran to give N-protected aspartic acids and dipeptides in good yields without racemization.