141996-63-6

Basic information

• Product Name: L-Aspartic acid, N-(3,3,3-trifluoro-2-methoxy-1-oxo-2-phenylpropyl)-, (R)-
• CAS NO: 141996-63-6
• Molecular Formula: C14H14F3NO6
• Molecular Weight: 349.263
• Mol File: 141996-63-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Aspartic acid, N-(3,3,3-trifluoro-2-methoxy-1-oxo-2-phenylpropyl)-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Aspartic acid, N-(3,3,3-trifluoro-2-methoxy-1-oxo-2-phenylpropyl)-, (R)-(141996-63-6)
• EPA Substance Registry System: L-Aspartic acid, N-(3,3,3-trifluoro-2-methoxy-1-oxo-2-phenylpropyl)-, (R)-(141996-63-6)

Safety Data

• Hazardous Substances Data: 141996-63-6(Hazardous Substances Data)

Upstream product

• 39637-99-5 (S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride 
• 5269-42-1 L-Aspartic acid bis(trimethylsilyl) ester 

Downstream Products

• 105678-41-9 (R)-MTPA-(S)-Ala-OH 
• 105693-31-0 (R)-MTPA-(R)-Ala-OH 
• 141996-65-8 (R)-2-Methoxy-2-phenyl-3-trifluoropropanoyl-L-aspartic anhydride 

Relevant articles and documents

L-aspartic acid bis(trimethylsilyl) ester: A convenient starting material for the acylation of L-aspartic acid

Reaction of L-aspartic acid with excess of bis(trimethylsilyl)amine under reflux provides optically pure L-aspartic acid bis(trimethylsilyl) ester in quantitative yield. This silyl ester reacts with a variety of acylating reagens in tetrahydrofuran to give N-protected aspartic acids and dipeptides in good yields without racemization.