142009-82-3Relevant articles and documents
Preparation of chiral 5,6-trans-disubstituted phenanthrolines from phenanthroline-5,6-epoxide
Schoffers, Elke,Tran, Son Duc,Mace, Kristen
, p. 769 - 772 (2007/10/03)
A new preparative route to chiral aminoalcohol derivatives of 5,6-dihydro-1,10-phenanthroline is described. Ring opening of 1,10-phenanthroline-5,6-epoxide (1) with a variety of nitrogen nucleophiles was accomplished using magnesium perchlorate as an effective Lewis acid and compared to reactions catalyzed by alumina.