142068-27-7

Basic information

• Product Name: Benzoic acid, 4-[1-(benzoylhydrazono)ethyl]-, ethyl ester
• CAS NO: 142068-27-7
• Molecular Formula: C18H18N2O3
• Molecular Weight: 310.353
• Mol File: 142068-27-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-[1-(benzoylhydrazono)ethyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-[1-(benzoylhydrazono)ethyl]-, ethyl ester(142068-27-7)
• EPA Substance Registry System: Benzoic acid, 4-[1-(benzoylhydrazono)ethyl]-, ethyl ester(142068-27-7)

Safety Data

• Hazardous Substances Data: 142068-27-7(Hazardous Substances Data)

Upstream product

• 38430-55-6 ethyl-4-acetylbenzoate 
• 613-94-5 benzoic acid hydrazide 

Downstream Products

• 802566-87-6 ethyl 4-[(1S)-1-aminoethyl]benzoate 
• 142068-37-9 (S)-1-p-carboethoxyphenyl-1-(2-benzoylhydrazino)ethane 

Relevant articles and documents

Method for preparing chiral diphosphines

The invention concerns a method for preparing a compound of formula (1) wherein: A represents naphthyl or phenyl optionally substituted; and Ar1, Ar2independently represent a saturated or aromatic carbocyclic group, optionally substituted.

Catalytic asymmetric reductive amination of ketones via highly enantioselective hydrogenation of the C=N double bond

We describe a convenient, chemoselective asymmetric reductive amination procedure for the conversion of ketones to chiral hydrazines and amines. The key step in the three-step process is enantioselective DuPHOS-Rh-catalyzed hydrogenation of the C=N double bond of N-acylhydrazones. Detailed optimization studies revealed the effect of solvent, temperature, and the N- acyl group on the enantioselectivity and catalytic efficiency of the reaction. The reduction products, N-acylhydrazines, were converted to hydrazines or amines through hydrolysis or treatment with samarium(II) iodide, respectively.