142075-07-8

Basic information

• Product Name: methyl 2-phenylpyrrolidinecarboxylate
• CAS NO: 142075-07-8
• Molecular Weight: 205.257
• Mol File: 142075-07-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 2-phenylpyrrolidinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-phenylpyrrolidinecarboxylate(142075-07-8)
• EPA Substance Registry System: methyl 2-phenylpyrrolidinecarboxylate(142075-07-8)

Safety Data

• Hazardous Substances Data: 142075-07-8(Hazardous Substances Data)

Upstream product

• 111944-26-4 methyl-N-(4-bromo-4-phenylbutyl)carbamate 
• 250691-28-2 methyl pyrrolidinecarboxylate iminium cation 
• 591-51-5 phenyllithium 
• 17763-67-6 Phenyl triflate 
• 76460-88-3 N-methoxycarbonyl-2,3-dihydropyrrole 
• 1006-64-0 2-(phenyl)pyrrolidine 
• 79-22-1 methyl chloroformate 
• 111944-13-9 methyl N-bromo-N-(4-phenylbutyl)carbamate 
• 56475-80-0 N-(methoxycarbonyl)pyrrolidine 

Downstream Products

• 76403-42-4 2-Oxo-5-phenyl-pyrrolidine-1-carboxylic acid methyl ester 

Relevant articles and documents

Electrochemical Functional-Group-Tolerant Shono-type Oxidation of Cyclic Carbamates Enabled by Aminoxyl Mediators

An electrochemical method has been developed for α-oxygenations of cyclic carbamates by using a bicyclic aminoxyl as a mediator and water as the nucleophile. The mediated electrochemical process enables substrate oxygenation to proceed at a potential that is approximately 1 V lower than the redox potential of the carbamate substrate. This feature allows for functional-group compatibility that is inaccessible with conventional Shono oxidations, which proceed by direct electrochemical substrate oxidation. This reaction also represents the first α-functionalization of non-activated cyclic carbamates with oxoammonium oxidants.

Catalytic asymmetric arylation of N-substituted 2-pyrrolines with aryl triflates

Catalytic asymmetric arylation of 1-(alkoxycarbonyl)-2-pyrrolines (4) with aryl triflates (1) in benzene in the presence of a base and a palladium catalyst, prepared in situ by mixing Pd(OAc)2 and (R)-BINAP, gives optically active (R)-1-(alkoxycarbonyl)5-aryl-2-pyrrolines (5) of up to 83percent ee. together with the regioisomers 1-(alkoxycarbonyl)-5-aryl-3-pyrrolines (6).