14208-10-7

Basic information

• Product Name: DPX
• Synonyms: 1,1’-(1,4-phenylenebis(methylene))bis-pyridiniudibromide;1,1’-(p-phenylenedimethylene)bis(pyridiniumbromide);1,1’-(p-phenylenedimethylene)bis-pyridiniudibromide;1,1’-(p-phenylenedimethylene)di-pyridiniudibromide;HISTOMOUNT(TM);DPX;DPX MOUNTANT;DPX MOUNTANT FOR HISTOLOGY
• CAS NO: 14208-10-7
• Molecular Formula: 2Br*C₁₈H₁₈N₂
• Molecular Weight: 422.162
• EINECS: 215-535-7
• Product Categories: Embedding and Mounting Media;Embedding MediaHematology and Histology;Hematology and Histology Lab Accessories;Microscopy Reagents
• Mol File: 14208-10-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 296-297 °C(Solv: acetonitrile (75-05-8))
• Flash Point: 77 °F
• Appearance: white to off-white/
• Density: 0.904 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.521(lit.)
• Storage Temp.: 2-8°C
• Solubility: H2O: soluble
• CAS DataBase Reference: DPX(CAS DataBase Reference)
• NIST Chemistry Reference: DPX(14208-10-7)
• EPA Substance Registry System: DPX(14208-10-7)

Safety Data

• Hazard Codes: Xn,Xi,T,F
• Statements: 10-20/21-38-36/37/38-62-61-65-48/20-11
• Safety Statements: 26-36-45-36/37-53-25-62-16
• RIDADR: UN 1307 3/PG 3
• WGK Germany: 3
• RTECS: UU6857800
• Hazardous Substances Data: 14208-10-7(Hazardous Substances Data)

Usage

Description

N,N'-4-Xylylenebis(pyridinium), also known as D.P.X, is a mixture composed of distyrene (polystyrene), a plasticizer (tricresyl phosphate), and xylene. It is characterized by its ability to protect stains and its quick-drying properties, making it a versatile compound with various applications in different industries.

Uses

Used in Biomedical Research:
N,N'-4-Xylylenebis(pyridinium) is used as a mounting medium for the preservation and examination of tissue samples in various biological studies. It is particularly useful for maintaining the integrity and quality of the samples during the staining process, ensuring accurate results.
Used in Immunohistochemistry Studies:
N,N'-4-Xylylenebis(pyridinium) is used as a mounting medium for rat brain sections, mouse small intestine sections, and gastrointestinal tract sections of rats. It helps in the preservation of these tissues, allowing for the detection and localization of specific antigens within the tissue, which is crucial for understanding various biological processes and disease mechanisms.
Used in Morphometry Studies:
In addition to immunohistochemistry, N,N'-4-Xylylenebis(pyridinium) is also used as a mounting medium for morphometry studies involving mouse small intestine sections. Morphometry is the quantitative analysis of biological structures, and D.P.X helps in maintaining the structural integrity of the tissue samples, enabling accurate measurements and analysis.
Overall, N,N'-4-Xylylenebis(pyridinium) is a valuable compound in the field of biomedical research, particularly in the areas of immunohistochemistry and morphometry, due to its ability to protect stains and facilitate quick drying of tissue samples.

Upstream product

• 110-86-1 pyridine 
• 623-24-5 1,4-bis(bromomethyl)benzene 
• 27768-49-6 1,1’-bis(phenylmethyl)-4,4’bipyridinium bromide 

Downstream Products

• 623-27-8 terephthalaldehyde, 

Relevant articles and documents

Preparation and in vitro screening of symmetrical bispyridinium cholinesterase inhibitors bearing different connecting linkage-initial study for Myasthenia gravis implications

Reversible inhibitors (e.g., pyridostigmine bromide, neostigmine bromide) of carbamate origin are used in the early treatment of Myasthenia gravis (MG) to block acetylcholinesterase (AChE) native function and conserve efficient amount of acetylcholine for

Binding selectivity of cucurbit[7]uril: Bis(pyridinium)-1,4-xylylene versus 4,4′-bipyridinium guest sites

The binding interactions between the host cucurbit[7]uril (CB7) and a series of linear guests containing bis(pyridinium)-1,4-xylylene and/or 4,4′-bipyridinium residues were investigated by 1H NMR spectroscopy. CB7 was found to exhibit considerable binding selectivity for bis-(pyridinium)-1,4-xylylene over 4,4′-bipyridinium sites. New pseudo-rotaxane and rotaxane compounds were synthesized utilizing the host-guest interactions between CB7 and the surveyed guests.