1420834-43-0

Basic information

• Product Name: 3-[(2-bromo-thiazole-4-carbonyl)-amino]-3-o-tolyl-propionic acid methyl ester
• Synonyms: 3-[(2-bromo-thiazole-4-carbonyl)-amino]-3-o-tolyl-propionic acid methyl ester
• CAS NO: 1420834-43-0
• Molecular Weight: 383.266
• Mol File: 1420834-43-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-[(2-bromo-thiazole-4-carbonyl)-amino]-3-o-tolyl-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(2-bromo-thiazole-4-carbonyl)-amino]-3-o-tolyl-propionic acid methyl ester(1420834-43-0)
• EPA Substance Registry System: 3-[(2-bromo-thiazole-4-carbonyl)-amino]-3-o-tolyl-propionic acid methyl ester(1420834-43-0)

Safety Data

• Hazardous Substances Data: 1420834-43-0(Hazardous Substances Data)

Upstream product

• 5198-88-9 2-bromothiazole-4-carboxylic Acid 
• 1009692-04-9 3-amino-3-o-tolyl-propionic acid methyl ester 

Downstream Products

• 1420834-45-2 3-[(2-bromo-thiazole-4-carbonyl)-amino]-3-o-tolyl-propionic acid 

Relevant articles and documents

3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS

The present invention relates to compounds of the formula I, wherein Ht, G, R10, R30, R40, R50 and R60 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. They are inhibitors of the protease cathepsin A, and are useful for the treatment of diseases such as atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases, for example. The invention furthermore relates to processes for the preparation of the compounds of the formula I, their use and pharmaceutical compositions comprising them.

3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS

3-Heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals The present invention relates to compounds of the formula I, wherein Ht, G, R10, R30, R40, R50 and R60 have the meanings