1420990-58-4

Basic information

• Product Name: C₂₁H₁₆F₂N₆O₂S
• CAS NO: 1420990-58-4
• Molecular Weight: 454.46
• Mol File: 1420990-58-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₆F₂N₆O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₆F₂N₆O₂S(1420990-58-4)
• EPA Substance Registry System: C₂₁H₁₆F₂N₆O₂S(1420990-58-4)

Safety Data

• Hazardous Substances Data: 1420990-58-4(Hazardous Substances Data)

Upstream product

• 1420990-54-0 7-bromo-6-[(4-chloro-5H-1,2,3-dithiazol-5-ylidene)amino]quinazolin-4(3H)-one 
• 1420990-53-9 7-bromo-6-[(4-chloro-5H-1,2,3-dithiazol-5-ylidene)amino]quinazolin-4(3H)-one 
• 1420990-52-8 3-benzyl-7-bromo-6-[(4-chloro-5H-1,2,3-dithiazol-5-ylidene)amino]quinazolin-4(3H)-one 
• 1420990-51-7 6-amino-3-benzyl-7-bromoquinazolin-4(3H)-one 
• 1420990-50-6 3-benzyl-7-bromo-6-nitroquinazolin-4(3H)-one 
• 451494-34-1 7-bromo-6-nitroquinazolin-4(3H)-one 
• 194851-16-6 7-bromoquinazolin-4(3H)-one 
• 99277-71-1 4-bromo-2-nitrobenzoic acid 
• 1420990-55-1 1,3-thiazolo[4,5-g]quinazolin-8(7H)-one 
• 124627-86-7 1-(((2R,3S)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)-methyl)-1H-1,2,4-triazole 

Relevant articles and documents

Discovery of a novel broad-spectrum antifungal agent derived from albaconazole

Synthesis of a strict structural analogue of albaconazole in which the quinazolinone ring is fused by a thiazole moiety led to the discovery of a new triazole with broad-spectrum antifungal activity. Compound I exhibited high in vitro activity against pathogenic Candida species and filamentous fungi and showed preliminary in vivo antifungal efficacy in a mice model of systemic candidiasis.