1422655-40-0

Basic information

• Product Name: 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl (2-cyanobenzo[d]thiazol-6-yl)carbamate
• Synonyms: 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl (2-cyanobenzo[d]thiazol-6-yl)carbamate
• CAS NO: 1422655-40-0
• Molecular Weight: 435.311
• Mol File: 1422655-40-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl (2-cyanobenzo[d]thiazol-6-yl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl (2-cyanobenzo[d]thiazol-6-yl)carbamate(1422655-40-0)
• EPA Substance Registry System: 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl (2-cyanobenzo[d]thiazol-6-yl)carbamate(1422655-40-0)

Safety Data

• Hazardous Substances Data: 1422655-40-0(Hazardous Substances Data)

Upstream product

• 7724-12-1 2-cyano-6-aminobenzothiazole 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 302348-51-2 (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol 
• 1334019-92-9 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyloxycarbonyl chloride 

Downstream Products

• 7724-12-1 2-cyano-6-aminobenzothiazole 
• 1476735-93-9 4-((2-cyanobenzo[d]thiazol-6-ylcarbamoyloxy)methyl)phenylboronic acid 

Relevant articles and documents

A sequentially activated bioluminescent probe for observation of cellular H2O2production induced by cysteine

We report herein a caged luciferin probeCy-Hyas a sequentially activated probe to selectively and sensitively sensel-Cys and H2O2. The probe displayed fluorescence and bioluminescence responses toward the two analytes. Utilizing the present probe, cellular excessl-Cys-induced H2O2up-regulation was observed for the first time in living MDA-MB-231 cells.

Luciferin Derivatives from Bicyclic Reactants and Aminothiol Derivatives and Methods of Use Thereof

The present disclosure features a condensation reaction and a luciferin-unmasking reaction that can be carried out under physiological conditions. In general, the condensation reaction involves reacting a bicyclic reactant with an aminothiol derivative, generating a luciferin or luciferin derivative. A luciferin can provide detectable luminescence. A luciferin derivative can be unmasked to provide detectable luminescence in a luciferin-unmasking reaction. The present disclosure provides bicyclic reactants and aminothiol derivatives suitable for use in the condensation reaction. The condensation and luciferin-unmasking reactions find use in a variety of applications, which are also provided.