142285-73-2

Basic information

• Product Name: N-benzyl-N-(2-<1,4>benzodioxanylmethyl)-N-(3-chloropropyl)amine hydrochloride
• Synonyms: N-benzyl-N-(2-<1,4>benzodioxanylmethyl)-N-(3-chloropropyl)amine hydrochloride
• CAS NO: 142285-73-2
• Molecular Weight: 368.303
• Mol File: 142285-73-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-benzyl-N-(2-<1,4>benzodioxanylmethyl)-N-(3-chloropropyl)amine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-N-(2-<1,4>benzodioxanylmethyl)-N-(3-chloropropyl)amine hydrochloride(142285-73-2)
• EPA Substance Registry System: N-benzyl-N-(2-<1,4>benzodioxanylmethyl)-N-(3-chloropropyl)amine hydrochloride(142285-73-2)

Safety Data

• Hazardous Substances Data: 142285-73-2(Hazardous Substances Data)

Upstream product

• 74398-46-2 3-[(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-amino]-propan-1-ol 
• 100-44-7 benzyl chloride 

Relevant articles and documents

Synthesis, antihypertensive and α-adrenoceptor activity of novel 2-aminoalkyl-3(2H)-pyridazinones

A number of 2-phenoxyalkylaminoalkyl- and 2-[1,4]benzodioxanylmethylaminoalkyl-3(2H)-pyridazinones were synthesized and tested for hypotensive and antihypertensive activity as well as for α1- and α2-adrenoceptor binding affinities. S

3(2H)-pyridazinone derivatives, a process and intermediates for preparing them and medicaments containing them and/or other 3(2H)-pyridazinone derivatives

The subject-matter of the invention are 3(2H)-Pyridazinone derivatives of the general formula wherein R stands for an ethyl or propyl group substituted by a terminal halogen atom or hydroxyl group or a terminal group of the formula in which latter R? represents a hydrogen atom or an optionally substituted benzyl group and R? represents a hydrogen atom or an optionally substituted benzo[1,4]dioxan-2-yl-methyl or benzo[1,4]dioxan-2-yl-ethyl group or a group of the formula in which latter n is 2 or 3 and R? stands for an optionally substituted phenoxy or phenylthio group and X stands for a hydrogen or halogen atom or an optionally substituted saturated or unsaturated 5-or 6-membered heterocyclic group.Furthermore the subject-matter of the invention are a process and intermediates for preparing these compounds and medicaments containing them and/or other 3(2H)-pyridazinone derivatives.The compounds according to the invention inhibit the adrenergic alpha? receptors, have a calcium--antagonistic effect and exert blood pressure lowering action.