142312-14-9Relevant articles and documents
AMIDOALKYLATION OF PYRAZINE-2,3-DICARBONITRILE BY THE RADICAL GENERATED FROM N-ALKANOYLANILINOALKANOIC ACID
Tada, Masaru,Furuse, Reiko,Kashima, Hiroko
, p. 357 - 362 (2007/10/02)
N-alkanoylanilinoacetic acid and 2-N-alkanoylanilinopropionic acid gave N-alkanoylanilinomethyl radical and 1-N-alkanoylanilinoethyl radical respectively by the oxidation catalyzed by silver ion.The former radical reacts with pyrazine-2,3-dicarbonitrile to give both monosubstitution product (6) and disubstitution product (7), whereas the latter radical gives only monosubstitution product due to the steric hindrance for the second radical substitution.