142314-72-5

Basic information

• Product Name: METHYL 2-BROMOMETHYL-3-FLUORO-BENZOATE
• Synonyms: METHYL 2-BROMOMETHYL-3-FLUORO-BENZOATE;Benzoic acid, 2-(broMoMethyl)-3-fluoro-, Methyl ester
• CAS NO: 142314-72-5
• Molecular Formula: C₉H₈BrFO₂
• Molecular Weight: 247.06
• Mol File: 142314-72-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 301.3±37.0 °C(Predicted)
• Appearance: /
• Density: 1.534±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: METHYL 2-BROMOMETHYL-3-FLUORO-BENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-BROMOMETHYL-3-FLUORO-BENZOATE(142314-72-5)
• EPA Substance Registry System: METHYL 2-BROMOMETHYL-3-FLUORO-BENZOATE(142314-72-5)

Safety Data

• Hazardous Substances Data: 142314-72-5(Hazardous Substances Data)

Usage

General Description

Methyl 2-bromomethyl-3-fluoro-benzoate is an organic chemical compound characterized as a benzoate ester and an organobromide. It contains bromine and fluorine atoms attached to a benzene ring structure. The benzoate group in this compound is a common structural component in many pharmaceutical drugs and is known for its antimicrobial and antifungal properties. This chemical is considered a specialized reagent and is likely used in various chemical reactions within laboratory settings, although its specific applications aren't directly listed. As with all chemicals, it should be handled with caution and appropriate safety measures due to potential hazards associated with its use.

Upstream product

• 230301-81-2 methyl 3-fluoro-2-methylbenzoate 
• 699-90-1 3-fluoro-2-methylbenzoic acid 

Downstream Products

• 642408-51-3 3-fluoro-2-[({4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-phenyl-amino)-methyl]-benzoic acid methyl ester 
• 230301-82-3 methyl 2-(cyanomethyl)-3-fluorobenzoate 
• 1407232-87-4 (S)-3-cyclohexyl-2-(4-fluoro-1-oxo-1,3-dihydro-isoindol-2-yl)-N-[1-(2-methoxy-ethyl)-1H-pyrazol-3-yl]-propionamide 
• 1407232-88-5 (S)-3-cyclohexyl-2-(4-fluoro-1-oxo-1,3-dihydro-isoindol-2-yl)-propionic acid methyl ester 
• 230301-83-4 5-fluoro-3,4-dihydro-2H-isoquinolin-1-one 

Relevant articles and documents

Spirocyclic tetrahydroquinazolines

The invention discloses spirocyclic tetrahydroquinazolines , and particularly provide compounds represented by Formula I shown in the specification, and pharmaceutically acceptable salts and solvates thereof. In the formula, R3, A, A1, A2, A3, E, E1, E2, L, Q, Z and a structure shown in the specification are as defined in the specification,. The compounds of formula I are KRAS inhibitors and are therefore useful in the treatment of cancer and other diseases.

OXOINDOLINE DERIVATIVES AS PROTEIN FUNCTION MODULATORS

The present invention provides chimeric compounds of formula (II) that modulate protein function, to restore protein homeostasis, including cytokine, aiolos, and/or ikaros activity, TNF-alpha activity, CKl-alpha activity and cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other cytokine and inflammatory mediators, are provided. Methods of treatment, amelioration, or prevention of protein-mediated diseases, disorders, and conditions, such as cytokine-mediated diseases, disorders, and conditions, including inflammation, fibromyalgia, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, inflammatory bowel diseases, Crohn's disease, ulcerative colitis, uveitis, inflammatory lung diseases, chronic obstructive pulmonary disease, Alzheimer's disease, organ transplant rejection, and cancer, are provided.

Tetrahydrobenzindole derivatives

Compounds containing tetrahydrobenzindole which bind to serotonin receptor and are useful in treatment or prevention of disease induced by abnormality of central peripheral serotonin controlling functions.