142342-78-7 Usage
Description
(S)-3-AMINO-4-METHYLPENTANOIC ACID ETHYL ESTER, with the molecular formula C8H17NO2, is a chiral chemical compound that is the ethyl ester of (S)-3-amino-4-methylpentanoic acid, an amino acid derivative. (S)-3-AMINO-4-METHYLPENTANOIC ACID ETHYL ESTER is known for its unique biological and chemical properties due to its chiral nature, with the (S)-enantiomer being particularly significant. Its structure and properties render it a versatile building block in organic chemistry and a valuable asset in the pharmaceutical industry.
Uses
Used in Pharmaceutical Synthesis:
(S)-3-AMINO-4-METHYLPENTANOIC ACID ETHYL ESTER is used as a key intermediate for the synthesis of various pharmaceuticals, particularly those targeting the central nervous system. Its unique structure allows for the development of drugs with specific therapeutic effects and improved pharmacological profiles.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (S)-3-AMINO-4-METHYLPENTANOIC ACID ETHYL ESTER serves as a crucial building block for the design and development of novel drug candidates. Its chiral nature and chemical properties make it an attractive option for creating enantiomerically pure compounds with potential applications in treating a range of medical conditions.
Used in Organic Chemistry:
(S)-3-AMINO-4-METHYLPENTANOIC ACID ETHYL ESTER is also utilized as a versatile reagent in organic chemistry, where it can be employed in various reactions to synthesize a wide array of chemical products. Its unique structure and properties make it a valuable tool for researchers in the field of organic synthesis.
Used in Drug Discovery:
(S)-3-AMINO-4-METHYLPENTANOIC ACID ETHYL ESTER's specific biological and chemical properties make it a promising candidate for drug discovery. Researchers can leverage its unique characteristics to identify new therapeutic targets and develop innovative treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 142342-78-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,3,4 and 2 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 142342-78:
(8*1)+(7*4)+(6*2)+(5*3)+(4*4)+(3*2)+(2*7)+(1*8)=107
107 % 10 = 7
So 142342-78-7 is a valid CAS Registry Number.
142342-78-7Relevant articles and documents
Turn Conformation of β-Amino Acid-Based Short Peptides Promoted by an Amidothiourea Moiety at C-Terminus
Zhang, Yanhan,Yan, Xiaosheng,Cao, Jinlian,Weng, Peimin,Miao, Daiyu,Li, Zhao,Jiang, Yun-Bao
, p. 9844 - 9849 (2020)
A C-terminal amidothiourea motif is shown to promote a β-turn-like folded conformation in a series of β-amino acid-based short peptides in both the solid state and solution phase by an intramolecular 11-membered ring hydrogen bond.
Scalable scny BRAnthesis of β-amino esters via reformatskcny BRA reaction with N-tert-butanesulfincny BRAl imines
Brinner, Kristin,Doughan, Brandon,Poon, Daniel J.
experimental part, p. 991 - 993 (2009/10/10)
The Reformatskcny BRA reagents derived from ethcny BRAl bromoacetate and tert-butcny BRAl bromoacetate add cleanlcny BRA, in high cny BRAield, and with good diastereoselectivitcny BRA to N-tert-butanesulfincny BRAl aldimines and ketimines. Importantlcny BRA, this reaction scales well (>50 mmol), and affords products upwards of 70% cny BRAield over three steps, starting from commerciallcny BRA available N-tert-butanesulfinamide, aldehcny BRAdes, and ketones.
Stereoselective reduction of enantiopure β-enamino esters by hydride: A convenient synthesis of both enantiopure β-amino esters
Cimarelli, Cristina,Palmieri, Gianni
, p. 5557 - 5563 (2007/10/03)
The reduction of enantiopure β-enamino esters 1 with sodium triacetoxyborohydride in acetic acid is described. This occurs with good diastereo- and enantioselectivity to yield β-amino esters 2 and 3 (after hydrogenolysis of the N-chiral group). A model is
