142434-21-7

Basic information

• Product Name: O-(5-acetamido-3,5-didesoxy-D-glycero-β-D-galacto-2-nonulopyranosylonsaeure)-(2->3)-O-β-D-galactopyranosyl-(1->3)-2-acetamido-2-desoxy-D-galactopyranose
• CAS NO: 142434-21-7
• Molecular Weight: 674.61
• Mol File: 142434-21-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: O-(5-acetamido-3,5-didesoxy-D-glycero-β-D-galacto-2-nonulopyranosylonsaeure)-(2->3)-O-β-D-galactopyranosyl-(1->3)-2-acetamido-2-desoxy-D-galactopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: O-(5-acetamido-3,5-didesoxy-D-glycero-β-D-galacto-2-nonulopyranosylonsaeure)-(2->3)-O-β-D-galactopyranosyl-(1->3)-2-acetamido-2-desoxy-D-galactopyranose(142434-21-7)
• EPA Substance Registry System: O-(5-acetamido-3,5-didesoxy-D-glycero-β-D-galacto-2-nonulopyranosylonsaeure)-(2->3)-O-β-D-galactopyranosyl-(1->3)-2-acetamido-2-desoxy-D-galactopyranose(142434-21-7)

Safety Data

• Hazardous Substances Data: 142434-21-7(Hazardous Substances Data)

Upstream product

• 489-52-1 lacto-N-biose 
• 117177-11-4 Benzyl-O-(5-acetamido-3,5-didesoxy-D-glycero-α-D-galacto-2-nonulopyranosylonsaeure)-(2->3)-O-<(2,6-di-O-(α-(2)H2)benzyl-β-D-galactopyranosyl>-(1->3)-2-acetamido-4,6-di-O-(α-(2)H2)benzyl-2-desoxy-β-D-galactopyranosid 
• 117177-11-4 Benzyl-O-(5-acetamido-3,5-didesoxy-D-glycero-β-D-galacto-2-nonulopyranosylonsaeure)-(2->3)-O-<(2,6-di-O-(α-(2)H2)benzyl-β-D-galactopyranosyl>-(1->3)-2-acetamido-4,6-di-O-(α-(2)H2)benzyl-2-desoxy-β-D-galactopyranosid 

Relevant articles and documents

The use of porcine liver (2->3)-α-sialyltransferase in the large-scale synthesis of α-Neup5Ac-(2->3)-β-D-Galp-(1->3)-D-GlcpNAc, the epitope of the tumor-associated carbohydrate antigen CA 50

α-Neup5Ac-(2->3)-β-D-Galp-(1->3)-D-GlcpNAc (2) and, α-Neup5Ac-(2->3)-β-D-Galp-(1->3)-β-D-GlcpNAcOMBn were prepared on a large scale by the action of β-D-Galp-(1->3)-D-GalpNAc (2->3)-α-sialyltransferase (partially purified from porcine liver) on β-D-Galp-(1->3)-D-GlcpNAc and β-D-Galp-(1->3)-β-D-GlcpNAcOMBn, respectively.The trisaccharide 2 is the epitope of the tumor-associated carbohydrate antigen CA 50, highly expressed in human pancreatic adenocarcinoma.