1425052-42-1

Basic information

• Product Name: 4,4,4-trifluoro-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide
• Synonyms: 4,4,4-trifluoro-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide
• CAS NO: 1425052-42-1
• Molecular Weight: 371.178
• Mol File: 1425052-42-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4,4,4-trifluoro-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4,4-trifluoro-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide(1425052-42-1)
• EPA Substance Registry System: 4,4,4-trifluoro-2-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide(1425052-42-1)

Safety Data

• Hazardous Substances Data: 1425052-42-1(Hazardous Substances Data)

Upstream product

• 651-83-2 4-trifluoromethyl-2,3,5,6-tetrafluoroaniline 
• 99783-23-0 4,4,4-trifluoro-2-methylbutanoic acid 
• 136564-78-8 2-methyl-4,4,4-trifluorobutyryl chloride 

Downstream Products

• 1425052-54-5 N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-2-(2,2,2-trifluoroethyl)-5-(triisopropylsilyl)pent-4-ynamide 

Relevant articles and documents

Ligand-Enabled Cross-Coupling of C(sp3)-H Bonds with Arylsilanes

Pd(II)-catalyzed cross-coupling of C(sp3)-H bonds with organosilicon coupling partners has been achieved for the first time. The use of a newly developed quinoline-based ligand is essential for the cross-coupling reactions to proceed.

Palladium(0)-catalyzed alkynylation of C(sp3)-H bonds

The alkynylation of β-C(sp3)-H bonds in aliphatic amides with alkynyl halides has been enabled using Pd(0)/N-heterocyclic carbene (NHC) and Pd(0)/phosphine (PR3) catalysts. This is the first example of utilizing [AlkynylPd(II)Ln