142534-58-5Relevant articles and documents
Synthesis and biological activity of phosphatidylinositol-3,4,5-trisphosphorothioate
Zhang, Honglu,Xu, Yong,Markadieu, Nicolas,Beauwens, Renaud,Erneux, Christophe,Prestwich, Glenn D.
, p. 762 - 766 (2008/09/19)
Metabolically-stabilized analogs of PtdIns(3,4,5)P3 have shown long-lived agonist activity for cellular events mediated by this phosphoinositide. We describe an efficient method for the total asymmetric synthesis of the trisphosphorothioate (PT
General synthesis of phosphatidylinositol 3-phosphates
Bruzik, Karol S.
, p. 2415 - 2418 (2007/10/02)
Uniform synthetic approach to phosphatidylinositol 3-phosphate, 3,4-bisphosphate and 3,4,5-trisphosphate has been elaborated starting from 1D-1-O-tert-butyldiphenylsilyl- and 1,6-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-myo-inositols using regioselec