14255-87-9 Usage
Description
Parbendazole is a benzimidazole carbamate that exists as crystals or a fine white powder. It is a potent inhibitor of microtubule assembly and functions, which makes it effective against various parasites. As a solid with specific chemical properties, Parbendazole has found applications in the pharmaceutical and veterinary industries.
Uses
Used in Pharmaceutical Industry:
Parbendazole is used as an antiparasitic agent for treating infections caused by various parasites, such as helminths and protozoa. Its ability to inhibit microtubule assembly and functions disrupts the normal growth and reproduction of parasites, leading to their elimination from the host organism.
Used in Veterinary Medicine:
In the veterinary field, Parbendazole is used as a deworming agent for livestock and pets. It helps in the treatment and prevention of parasitic infections in animals, ensuring their overall health and well-being. The use of Parbendazole in veterinary medicine contributes to the control of parasitic diseases and the improvement of animal productivity.
Used in Research:
Parbendazole is also utilized in research settings as a tool to study the role of microtubules in cellular processes. Its inhibitory effects on microtubule assembly make it a valuable compound for investigating the mechanisms underlying cell division, intracellular transport, and other microtubule-dependent functions. This research can provide insights into the development of new therapeutic strategies for various diseases, including cancer and neurodegenerative disorders.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Parbendazole is a carbamate ester-amine. Amines behave as chemical bases. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition Parbendazole emits toxic fumes.
Fire Hazard
Flash point data for Parbendazole are not available; however, Parbendazole is probably combustible.
Check Digit Verification of cas no
The CAS Registry Mumber 14255-87-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,2,5 and 5 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 14255-87:
(7*1)+(6*4)+(5*2)+(4*5)+(3*5)+(2*8)+(1*7)=99
99 % 10 = 9
So 14255-87-9 is a valid CAS Registry Number.
InChI:InChI=1/C13H17N3O2/c1-3-4-5-9-6-7-10-11(8-9)15-12(14-10)16-13(17)18-2/h6-8H,3-5H2,1-2H3,(H2,14,15,16,17)