1426022-42-5

Basic information

• Product Name: 2-methoxy-4-(2-phenylpyridin-4-yl)phenol
• Synonyms: 2-methoxy-4-(2-phenylpyridin-4-yl)phenol
• CAS NO: 1426022-42-5
• Molecular Weight: 277.323
• Mol File: 1426022-42-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methoxy-4-(2-phenylpyridin-4-yl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-4-(2-phenylpyridin-4-yl)phenol(1426022-42-5)
• EPA Substance Registry System: 2-methoxy-4-(2-phenylpyridin-4-yl)phenol(1426022-42-5)

Safety Data

• Hazardous Substances Data: 1426022-42-5(Hazardous Substances Data)

Upstream product

• 20649-42-7 coniferaldehyde 
• 19433-17-1 (E)‐1‐phenylethan‐1‐one O‐acetyl oxime 

Relevant articles and documents

Modular pyridine synthesis from oximes and enals through synergistic copper/iminium catalysis

We describe here a [3+3]-type condensation reaction of O-acetyl ketoximes and α,β-unsaturated aldehydes that is synergistically catalyzed by a copper(I) salt and a secondary ammonium salt (or amine). This redox-neutral reaction allows modular synthesis of a variety of substituted pyridines under mild conditions with tolerance of a broad range of functional groups. The reaction is driven by a merger of iminium catalysis and redox activity of the copper catalyst, which would initially reduce the oxime N-O bond to generate a nucleophilic copper(II) enamide and later oxidize a dihydropyridine intermediate to the pyridine product.