142653-11-0

Basic information

• Product Name: 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-7-methoxy-2-methyl-
• CAS NO: 142653-11-0
• Molecular Formula: C19H16ClNO4
• Molecular Weight: 357.793
• Mol File: 142653-11-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-7-methoxy-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-7-methoxy-2-methyl-(142653-11-0)
• EPA Substance Registry System: 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-7-methoxy-2-methyl-(142653-11-0)

Safety Data

• Hazardous Substances Data: 142653-11-0(Hazardous Substances Data)

Upstream product

• 1192805-29-0 N-(but-1-en-3-yl)-6-ethenyl-2-methoxy-N-p-toluenesulfonylaniline 
• 1192805-50-7 C₁₇H₁₇NO₃S 
• 53512-46-2 2-methyl-7-methoxy indole 
• 1398631-78-1 C₂₆H₂₂ClNO₄ 

Relevant articles and documents

Design and synthesis of indomethacin analogues that inhibit P-glycoprotein and/or multidrug resistant protein without Cox inhibitory activity

We designed and synthesized conformationally restricted analogues and regioisomers of the nonsteroidal anti-inflammatory drug indomethacin. Evaluation of the inhibitory effects of these compounds on COX, P-glycoprotein, and multidrug resistance indicated that NSAIDS modulation of multidrug-resistant P-glycoprotein and multidrug-resistant protein-1 is not associated with COX-1 and COX-2 inhibitory activities.