1426582-59-3Relevant articles and documents
Cinchona alkaloid amides/dialkylzinc catalyzed enantioselective desymmetrization of aziridines with phosphites
Hayashi, Masashi,Shiomi, Noriyuki,Funahashi, Yasuhiro,Nakamura, Shuichi
, p. 19366 - 19369 (2013/02/23)
The first highly enantioselective desymmetrization of aziridines with phosphites has been developed. Excellent yields and enantioselectivities were observed for the reaction with various aziridines using a new class of readily accessible chiral catalysts derived from 9-amino-9-deoxy-epi-cinchona alkaloids. In studies probing the reaction mechanism, we observed some complexes for the cinchona alkaloid amide-Zn(II) by ESI-MS analysis.