142666-04-4 Usage
Description
(+)(-)-8,12-trans-9-oxo-prosta-5,14-dienoic acid is a prostaglandin, a class of chemical compounds that are eicosanoids derived from fatty acids. It plays a significant role in various physiological functions in the human body, particularly in inflammation, blood pressure regulation, smooth muscle contraction, and immune response. (+)(-)-8,12-trans-9-oxo-prosta-5,14-dienoic acid is also implicated in the pathogenesis of diseases such as cardiovascular diseases and cancer, making it a crucial target for drug development and disease management.
Uses
Used in Pharmaceutical Industry:
(+)(-)-8,12-trans-9-oxo-prosta-5,14-dienoic acid is used as a target for drug development due to its potent inflammatory effects and involvement in the regulation of various physiological processes. Research on this compound aims to understand its molecular mechanisms and develop potential therapeutic interventions targeting its biological pathways, which can help in the management of diseases like cardiovascular diseases and cancer.
Used in Medical Research:
In the field of medical research, (+)(-)-8,12-trans-9-oxo-prosta-5,14-dienoic acid serves as an important subject of study to explore its role in the pathogenesis of various diseases. Understanding its involvement in inflammation and other physiological processes can contribute to the advancement of knowledge and the development of new treatment strategies for related health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 142666-04-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,6,6 and 6 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 142666-04:
(8*1)+(7*4)+(6*2)+(5*6)+(4*6)+(3*6)+(2*0)+(1*4)=124
124 % 10 = 4
So 142666-04-4 is a valid CAS Registry Number.
InChI:InChI=1/C20H32O3/c1-2-3-4-5-6-9-12-17-15-16-19(21)18(17)13-10-7-8-11-14-20(22)23/h6-7,9-10,17-18H,2-5,8,11-16H2,1H3,(H,22,23)/b9-6+,10-7-/t17-,18+/m0/s1
142666-04-4Relevant articles and documents
Synthesis of a preclavulones analogous: (±) 8,12-trans-(5Z,14Z)-9-oxo-prosta-5,10,14-trienoic acid methyl ester via its 10-11 dihydroprecursor from allyl 2-oxo-cyclopentanecarboxylate
Leggeri,Di Giacomo,Papeo,Pirillo,Traverso
, p. 117 - 126 (2007/10/02)
In this paper we report a method to prepare the (±)-8,12-trans(5Z,14Z)-9-oxo-prosta-5,10,14-trienoic acid methyl ester 1, a 11-desoxyprostanoid correlated to the class of Preclavulones, via a new easy synthesis of its 10-11 dihydroprecursor 16 and through a general procedure for the conversion of these 10-11 dihydrocompounds to the unsaturated analogous derivatives.
