1426686-02-3

Basic information

• Product Name: N,N'-(3,6,9,12-tetraoxatetradecane-1,14-diyl)bis(5-(3,5-dimethylisoxazol-4-yl)-2-methylbenzenesulfonamide)
• Synonyms: N,N'-(3,6,9,12-tetraoxatetradecane-1,14-diyl)bis(5-(3,5-dimethylisoxazol-4-yl)-2-methylbenzenesulfonamide)
• CAS NO: 1426686-02-3
• Molecular Weight: 734.892
• Mol File: 1426686-02-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N'-(3,6,9,12-tetraoxatetradecane-1,14-diyl)bis(5-(3,5-dimethylisoxazol-4-yl)-2-methylbenzenesulfonamide)(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-(3,6,9,12-tetraoxatetradecane-1,14-diyl)bis(5-(3,5-dimethylisoxazol-4-yl)-2-methylbenzenesulfonamide)(1426686-02-3)
• EPA Substance Registry System: N,N'-(3,6,9,12-tetraoxatetradecane-1,14-diyl)bis(5-(3,5-dimethylisoxazol-4-yl)-2-methylbenzenesulfonamide)(1426686-02-3)

Safety Data

• Hazardous Substances Data: 1426686-02-3(Hazardous Substances Data)

Upstream product

• 10557-85-4 4-iodo-3,5-dimethylisoxazole 
• 5720-05-8 4-methylphenylboronic acid 
• 154822-65-8 3,5-dimethyl-4-(4-methylphenyl)isoxazole 
• 936074-44-1 5-(3,5-dimethylisoxazol-4-yl)-2-methylbenzene-1-sulfonyl chloride 
• 68960-97-4 1,14-diamino-3,6,9,12-tetraoxatetradecane 

Relevant articles and documents

BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME

Described herein are compounds capable of modulating one or more biomolecules substantially simultaneously, e.g., modulating two or more binding domains (e.g., bromodomains) on a protein or on different proteins. For example, in one aspect, a bivalent compound or a pharmaceutically acceptable salt, stereoisomer, metabolite, or hydrate thereof is provided. In another aspect, a method of treating a disease associated with a protein having tandem bromodomains in a patient in need thereof is provided. The method comprises administering to the patient the bivalent compound as described.