1427038-01-4

Basic information

• Product Name: [4R-4α,9β,9aα]-1,6-dioxo-4-phenyloctahydropyrido[2,1-c][1,4]oxazine-9-carboxylic acid methyl ester
• Synonyms: [4R-4α,9β,9aα]-1,6-dioxo-4-phenyloctahydropyrido[2,1-c][1,4]oxazine-9-carboxylic acid methyl ester
• CAS NO: 1427038-01-4
• Molecular Weight: 303.315
• Mol File: 1427038-01-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [4R-4α,9β,9aα]-1,6-dioxo-4-phenyloctahydropyrido[2,1-c][1,4]oxazine-9-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [4R-4α,9β,9aα]-1,6-dioxo-4-phenyloctahydropyrido[2,1-c][1,4]oxazine-9-carboxylic acid methyl ester(1427038-01-4)
• EPA Substance Registry System: [4R-4α,9β,9aα]-1,6-dioxo-4-phenyloctahydropyrido[2,1-c][1,4]oxazine-9-carboxylic acid methyl ester(1427038-01-4)

Safety Data

• Hazardous Substances Data: 1427038-01-4(Hazardous Substances Data)

Upstream product

• 56613-80-0 D-2-phenylglycinol 
• 1009051-59-5 (4R)-1,6-dioxo-4-phenyl-1,3,4,6,7,8-hexahydropyrido[2, 1-c][1,4]oxazine-9-carboxylic acid methyl ester 
• 762-42-5 dimethyl acetylenedicarboxylate 

Downstream Products

• 1427038-02-5 (2R,3S)-methyl 2-(benzylcarbamoyl)-1-((R)-2-hydroxy-1-phenylethyl)-6-oxopiperidine-3-carboxylate 
• 1427038-03-6 C₂₂H₂₄N₂O₅ 
• 1427038-04-7 (R)-2-((4aR,7aS)-6-benzyl-2,5,7-trioxooctahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)-2-phenylethyl acetate 
• 151213-40-0 (1S,6S)-2,8-diazabicyclo[4.3.0]nonane 

Relevant articles and documents

First way of enantioselective synthesis of moxifloxacin intermediate

A new method of enantioselective synthesis of (S,S)-2,8-diazobicyclo [4.3.0] nonane was found by using (R)-2-amino-2- phenyl-ethanol as chiral induction reagent. The entire synthetic process included 8 steps which were easy to operate with high yield. The purification method was only simple recrystallization or even used directly in the next step without further purification. The total yield was 29%.