14271-34-2

Basic information

• Product Name: 2-Butenoic acid, 3-(4-methylphenyl)-
• CAS NO: 14271-34-2
• Molecular Formula: C11H12O2
• Molecular Weight: 176.215
• Mol File: 14271-34-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Butenoic acid, 3-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenoic acid, 3-(4-methylphenyl)-(14271-34-2)
• EPA Substance Registry System: 2-Butenoic acid, 3-(4-methylphenyl)-(14271-34-2)

Safety Data

• Hazardous Substances Data: 14271-34-2(Hazardous Substances Data)

Upstream product

• 122-00-9 para-methylacetophenone 
• 623-48-3 ethyl iodoacetae 
• 3724-65-0 2-butenoic acid 
• 94853-53-9 ethyl 3-(4-methylphenyl)-2-butenoate 

Downstream Products

• 1195-32-0 1-methyl-4-isopropenylbenzene 
• 39027-57-1 3-(4-methylphenyl)butanoic acid 
• 144782-30-9 (E)-3-(4-methylphenyl)but-2-enoyl chloride 
• 947383-46-2 (E)-1-methyl-4-(1-nitroprop-1-en-2-yl)benzene 
• 1619940-93-0 (E)-1-methyl-4-(4,4,4-trifluorobut-2-en-2-yl)benzene 
• 1427204-62-3 C₁₄H₁₆N₂OS 
• 39599-18-3 6-(p-tolyl)-2-methyl-2-heptanol, trans- 
• 6090-01-3 3-(p-tolyl)-1-butanol 
• 43208-94-2 1-Iod-3-p-tolylbutan 
• 122-00-9 para-methylacetophenone 
• 34335-30-3 3-(4-carboxy-phenyl)-butyric acid 
• 4981-38-8 3-hydroxy-3-p-tolyl-butyric acid 
• 14161-83-2 1-phenyl-3-(p-tolyl)but-2-en-1-one 

Relevant articles and documents

Synergistic N-Heterocyclic Carbene/Palladium-Catalyzed [3 + 2] Annulation of Vinyl Enolates with 1-Tosyl-2-vinylaziridine

The synergistic combination of N-heterocyclic carbene organocatalysis and transition-metal catalysis for a formal [3 + 2] annulation between 3-substituted but-2-enoates and 1-tosyl-2-vinylaziridine was developed. This cooperative strategy provides a facile and efficient access to various functionalized (E)-3-ethylidene-4-vinylpyrrolidin-2-ones in a regioselective and stereoselective manner. The preliminary asymmetric studies were also performed, which indicated a potential for enantioselective annulation of vinyl enolate intermediates with transition-metal-π-allyl species.

N-Heterocyclic Carbene-Catalyzed Activation of Esters of N-Hydroxyphthalimide: A Highly Enantioselective Route to Chiral Dihydropyridinones Bearing an All Carbon Quaternary Stereogenic Center

An N-heterocyclic carbene-catalyzed highly enantioselective [3 + 3] annulation reaction of N-hydroxyphthalimide (NHPI) 3,3-disubstituted acrylates and N-Ts ketimines was developed. In most cases, the desired chiral dihydropyridinone products bearing an all carbon quaternary stereogenic center could be obtained in good yields with excellent enantioselectivities (>99% ee's), which demonstrated the NHPI acrylates as a kind of excellent substrate in NHC-catalysis.

N-heterocyclic carbene-catalyzed cyclization of unsaturated acyl chlorides and ketones

A straightforward synthesis of optically active trifluoromethyl dihydropyranones and spirocyclic oxindole-dihydropyranones has been realized by the chiral N-heterocyclic carbenes-catalyzed cyclization of α,β- unsaturated β-methylacyl chlorides with activated trifluoromethyl ketones or isatin derivatives. Copyright