142719-21-9Relevant articles and documents
Intramolecular Claisen-type Condensations of β-Acetoxy Amides or Imides
Brandaenge, Svante,Leijonmarck, Hans
, p. 3025 - 3028 (1992)
Intramolecular Claisen-type condensation of amide 1 or imide 7 leads to the same δ-lactone in racemic (2) or enantiomerically pure form (4) respectively.A side-reaction producing the 11-membered ring compound 6 makes imide 3 unsuitable as a starting material for the synthesis of 4.A clean two-step reduction of 4 to 9 is also described.